Abstract: This paper develop s a model of location and allocation in view of emergency with infection. Infection means when an emergency occurs in one place,the same emergency may occur in the places near it. The resource supply for the place where the emergency happens will influence the resource demand of the emergency elicited. So the demand of the whole place is combinations of demand. The model in this paper considers demand combinations and analyzes the problem in two stages and combines location and allocation in one model. Finally,this paper designs a two-layer tabu search algorithm and gives a numerical example.

Key words: infection effect, emergency, resource location and allocation, tahu search