Abstract: With the growth of the requirement for the quality and safety of the product, how to decrease the loss of the perishable foods as well as improve resource usage turns a key point.Since perishable items are sensitive to the time, and a part of them have different usages during the whole lifetime, the paper researches the distribution centers location problem in perishable it emslogistics network according to the transportation time and different needs of the retailers.With the assumption of Osvald and Stirn^[15], A PPMULP model is proposed, which is solved by the lagrange relaxation method.It is found that this algorithm is effective and efficient.Finally, it is concluded that considering perishable items' sensitivity to time and its multi-usage can decreases the costled by deterioration when compared with the situation which does not consider the two factors.

Key words: perishable product, multi-usage, capacity limitation, location